Modeling Spatial Variation in Leukemia Survival Data

نویسندگان

  • Robin Henderson
  • Silvia Shimakura
  • David Gorst
چکیده

In this article we combine ideas from spatial statistics with lifetime data analysis techniques to investigate possible spatial variation in survival of adult acute myeloid leukemia patients in northwest England. Exploratory analysis suggests both clinically and statistically signiŽ cant variation in survival rates across the region. A multivariate gamma frailty model incorporating spatial dependence is proposed and applied, with results conŽ rming the dependence of hazard on location.

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تاریخ انتشار 2003